That is a very broad question that has many answers, but for me separation from my family was the worst, and mostly because you feel like you've died and are forced to watch the world go on without you. It's an impossible position that only time will change, the time left in your sentence.
https://www.inmateaid.com/ask-the-inmate/what-is-the-worst-thing-about-prison#answer
Accepted Answer Date Created: October 15,2012